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Annals of Oncology - Fulltext: Volume 14(6) June 2003 p 864-866 A.
Oral eniluracil/5-FU was shown in early clinical studies to have encouraging . Promising early results of oral 5-fluorouracil plus eniluracil (776C85) in.

Institute of Cancer Research Repository - A study to evaluate the.
Concurrent administration of oral eniluracil with oral 5-FU not only increases . Conclusions: Eniluracil increases the oral bioavailability of 5-FU and.

Oral eniluracil/5-fluorouracil in patients with inoperable.
CONCLUSIONS: Eniluracil/5-FU as a 28-day oral outpatient regimen is well tolerated by patients with inoperable hepatocellular carcinoma, although minimal.

Original article A dose-escalating study of oral eniluracil/5.
cycle), and the dose intensity of oral eniluracil/5-FU was gradually increased by . oral eniluracil/5-FU twice daily for 14 days in combination with.

Methods for administering DPD inhibitors in combination with 5-FU.
Due to the structural similarity between eniluracil and 5-FU, eniluracil is a . 5-FU and 5-FU prodrugs to be effectively dosed by oral administration..

A Phase I Trial of Weekly Paclitaxel Plus Prolonged Oral.
Oral eniluracil/5-FU was administered orally twice daily for 28 consecutive days starting on day 1 of each cycle. Cycles were repeated every 35 days..

Unbound MEDLINE | Low-dose oral fluorouracil with eniluracil as.
Patients received oral 5-FU 1.0 mg/m(2) with eniluracil 10 mg/m(2), both given twice daily for the first 28 days of each 35-day cycle, continuing until.

ScienceDirect - The Lancet : Modulation of fluorouracil tissue.
In period 2, oral eniluracil (20 mg twice daily) was given on days 1–4,. Phase I and pharmacologic study of oral 5-FU on a chronic daily schedule in.

Mechanism-based inactivation of dihydropyrimidine dehydrogenase by.
Phase I Study of Eniluracil, a Dihydropyrimidine Dehydrogenase Inactivator, and Oral 5-Fluorouracil with Radiation Therapy in Patients with Recurrent or.

ACT Health - Research - TCH - Medical Oncology - Research.
A Phase I trial of escalating dose eniluracil/oral 5-fluorouracil plus oxaliplatin (OXA) in patients with advanced gastrointestinal malignancies..


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